Taking Lorazepam With Other Medicines And Herbal Supplements

Cautions with other medicines

Some medicines affect the way lorazepam works and increase the chances of you having side effects.

Speak to a doctor or pharmacist before starting to take lorazepam if you take any of these medicines:

antidepressants, used to treat depression
antipsychotics, used to treat mental health problems
anticonvulsants, used to treat seizures
hypnotics, used to treat anxiety or sleep problems
drowsy or sedating antihistamines, such as chlorphenamine or promethazine
strong painkillers, such as codeine, methadone, morphine, oxycodone, pethidine or tramadol
HIV medicines, such as ritonavir, atazanavir, efavirenz or saquinavir
rifampicin, a medicine for bacterial infections
antifungal medicines, such as fluconazole
proton pump inhibitors (PPIs) - medicines for reducing stomach acid, such as omeprazole or esomeprazole
muscle relaxants, such as baclofen or tizanidine
disulfiram, a medicine for alcohol addiction
isoniazid, a medicine for tuberculosis
theophylline, a medicine for asthma and other breathing problems

Mixing lorazepam with herbal remedies or supplements

Do not take herbal remedies for anxiety or insomnia, such as valerian or passionflower, with lorazepam. They can increase the drowsy effects of lorazepam and may also have other side effects.

There's not enough information to say that other complementary medicines, herbal remedies and supplements are safe to take with lorazepam. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

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